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World First Antioxidant DNA

Aptamin (Aptamer + Vitamins or Active Ingredients)

Aptamin is the world first DNA aptamer-based DNA-Vitamin(Antioxidants) complex compound developed by NEXMOS that dramatically improves the effects of active cosmetic, dietary supplements ingredients and more. Using a unique property of aptamer specifically binding, NEXMOS is developing a novel aptamers-antioxidant compound that maintaining reduced condition and slowly releasing antioxidant(Aptasensing). Aptamin will be a catalyst to change existing chemical-based cosmetics and nutritional supplement market to DNA(Bio)-based market.

Aptamin-C (Aptamer + Vitamin C), the first Aptamin complex by Nexmos that aptamer-based prevention of Vitamin C oxidation (Long-term maintenance of reduced ascorbic acid by Aptamer).

Concept of Aptamin

AA Aptamer

Antioxidants and Free Radicals

  • Antioxidants (good) Vitamin C is an electron donor to free radicals

  • Free radicals(bad) Caused by pollutions, UV light, stress

  • Cell damage stopped
    (Anti-aging effect)
    Neutralized, the atom becomes stable

Development of Aptamin Products

Innovation of Aptamin

  • New Delivery System

    Preventing oxidation of target ingredients (Antioxidants)
    - Maximum effect of antioxidants
    - Longer shelf life

  • Sustainability

    Slow release of target ingredients

  • Personalized Skin Care

    - Aptasensing: Innovative Bi-directional Smart
    - Cosmeceuticals Skin sensing (UV, pH, Temperature, ATP) → Target ingredients release

  • Solution of Safety Issues

    Safety issues resolution of chemical additives and derivatives

  • Stability in Water

    Maintenance of reduced Antioxidants in Water

  • Inhibition of Rancidity

    Prevention of oxidative decomposition

Aptamin Developments

Aptamin “Smart Skincare Products

Aptamin “Antioxidant Beverages & Foods

Aptamin “Preservative

Aptamin “Health Foods & Nutrition Supplements

Aptamin “Industrial Products
                 (Semiconductor Developments & High-Performance eco-batteries)

Aptamin is the Solution

Aptamin, the World First DNA-Antioxidants, developed by NEXMOS provides an innovative solution !

  • Many antioxidants have common problem of self-oxidation in the air.
  • They lose potency of antioxidant effect dramatically. So, it is very skeptical to expect long-term effects of products containing antioxidants.

Aptamin = the optimized choice stabilizing reduced Antioxidants

Aptamin Application List (2017)

  • Vitamin C

    • Reduce brown spots and other types of sun damage
    • Fade post-breakout red marks (Acne mark) by improving skin’s natural healing response
    • Reduce inflammation and irritation
    • Photoprotectant : Increase the effectiveness of sunscreens and boosts your skins defense against UV exposure
  • Astaxanthin

    • The best known natural lipid soluble antioxidant
    • Cross BBB – neuroprotective agent for clinical use
    • Improve immune function
    • Directly blocks a modest amount of ultraviolet light.
    • Neutralizes some of the free radicals induced by UV radiation.
    • Inhibit the induction of Matrix metalloproteinases (MMPs) by UV light. (MMPs are culprits for sun damage and skin aging.)
    • Well absorbed if applied topically (e.g. in a cream or lotion)
  • Resveratrol

    • A member of a family of compounds known as wine polyphenols.
      When taken orally, it may boost healthy life span by activating “longevity genes.” Anti-aging
    • Potent antioxidant - free radical scavenger - protect against sun damage, greater than vitamin A,C and E.
    • 17-fold greater antioxidant potency than idebenone ( Prevage MD® )
    • Cardiovascular benefit, possible benefit of Alzheimer Disease
    • Phyto hormonal effects
  • Vitamin A (Retinol)

    • All retinoids convert to retinoic acid in cells working for retinoid receptors.
    • All retinoids have different efficacy for different retinoid receptors.
    • Proven to improve fine lines, wrinkles and other signs of skin aging (age spot).
    • Acne treatment / Anti wrinkle therapy
  • Catechin Polyphenol (EGCG)

    • Antioxidant
    • Anti-aging skin benefit: protection from skin cancer / reduce sun damage. Green tea may synergistically enhance sun protection when used in addition to a sunscreen.
    • Gallocatechin(GC), Epigallocatechin(EGC), Epicatechin(EC), and Epigallocatechin gallate(EGCG).
  • Coenzyme Q10

    • Antioxidant : boost skin repair and regeneration and reduce free radical damage.
    • There are many studies in progress and CoQ10 will probably play an important role in preventing ageing of the skin, and its effects will be certified by the regulatory agencies of Europe(EFSA) and the United States(FDA).
  • Additional Applications

    • Vitamin E (Tocopherol), Hydroquinone, Ergothioneine, Lutein, Saponin, Caffeine